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SELECT ?title WHERE { ?? (rdfs:label|skos:prefLabel|schema:name) ?title . } Keimbahn-Gentherapie

SELECT ?class WHERE { ?? (rdf:type|owl:type) ?class . } DefinedTerm, Term, Validated Entry

SELECT ?description WHERE { ?? (rdfs:comment|schema:description) ?description . } Form der Gentherapie, bei der Gene mit Methoden der Gentechnologie in befruchtete Eizellen eingeschleust werden, um mutierte Gene zu ersetzen oder zu inaktivieren, wobei die übertragenen Gene weitervererbt werden können.

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Attributes

Name
Keimbahn-Gentherapie
Name
germline gene therapy
Name
thérapie génique des cellules germinales
Name
terapia genica delle cellule germinali
Description
Form der Gentherapie, bei der Gene mit Methoden der Gentechnologie in befruchtete Eizellen eingeschleust werden, um mutierte Gene zu ersetzen oder zu inaktivieren, wobei die übertragenen Gene weitervererbt werden können.
Description
Gene therapy that involves modifying the genes in egg or sperm cells, which will then pass any genetic changes to future generations.
Description
Manipulation du génome constitutionnel par correction dans une cellule germinale ou dans une cellule de l'embryon précoce, entraînant une transmission à la descendance.
Description
Terapia genica che implica l'inserimento deliberato di un gene nelle cellule germinali (con trasmissione dei geni di entrambi i genitori alla prole), la soppressione di un gene da queste o l'alterazione di un gene già presente.
dateModified
2021-06-16T10:28:13.4170000Z
Identifier
66487
URL
https://www.termdat.bk.admin.ch/entry/66487
citation
CORDIS - Risultati di ricerca dell'UE, Terapia genica - Il gran dibattito, 1997-10-08 ([Internet, 2021-04-20](https://cordis.europa.eu/article/id/9143-gene-therapy-the-great-debate/it))
citation
Spektrum.de, Lexikon der Biologie, "Keimbahntherapie" ([Internet, 2021-04-20](https://www.spektrum.de/lexikon/biologie/keimbahntherapie/35721))
citation
Swiss Expert Committee for Biosafety, Topics > Gene therapy, 2021-01-04 ([Internet, 2021-04-20](https://www.efbs.admin.ch/en/topics/gene-therapy/))
citation
Le grand dictionnaire terminologique, "génothérapie germinale" ([Internet, 2021-04-20](http://gdt.oqlf.gouv.qc.ca/ficheOqlf.aspx?Id_Fiche=17010858))
position
1
Term Note
EXP: da sich Keimbahneingriffe auf die nächsten Generationen (unvorhersehbar) auswirken (können), löst die Keimbahntherapie am Menschen ethische Debatten aus (a); sie ist in der Schweiz verboten (b)
Term Note
EXP: although it has potential for preventing inherited disease, germline gene therapy is controversial and very little research is being done, for technical and ethical reasons (a); it is prohibited in Switzerland (b)
Term Note
EXP: cette génothérapie est inapplicable à l'humain pour des raisons techniques et éthiques (a); elle est interdite en Suisse (b)
Term Note
EXP: essa prevede l'ereditarietà delle modifiche genetiche attuate e risulta quindi impraticabile e improponibile per un complesso di ragioni di natura tecnica, scientifica, sociale, ma soprattutto giuridica ed etica (a); è vietata in Svizzera (b)
termNoteCitation
(a) nach Chr. G. Bern, Genome Editing in Zeiten von CRISPR/Cas - Eine rechtliche Analyse, C. Ethische Kontroverse über die Keimbahntherapie am Menschen, 2020, S. 22 ([Internet, 2021-04-20](https://www.peterlang.com/view/9783631818558/html/ch12.xhtml)); (b) Eidgenössische Fachkommission für biologische Sicherheit, Themen > Gentherapie, 2021-01-04 ([Internet, 2021-04-20](https://www.efbs.admin.ch/de/themen/gentherapie/))
termNoteCitation
(a) KidsHealth, For Parents > Gene Therapy and Children - Two Types of Gene Therapy, 2021 ([Internet, 2021-04-20](https://kidshealth.org/en/parents/gene-therapy.html)); (b) Swiss Expert Committee for Biosafety, Topics > Gene therapy, 2021-01-04 ([Internet, 2021-04-20](https://www.efbs.admin.ch/en/topics/gene-therapy/))
termNoteCitation
(a) Le grand dictionnaire terminologique, "génothérapie germinale" ([Internet, 2021-04-20](http://gdt.oqlf.gouv.qc.ca/ficheOqlf.aspx?Id_Fiche=17010858)); (b) Commission fédérale d'experts pour la sécurité biologique, Thèmes > Thérapie génique, 2021-01-04 ([Internet, 2021-04-20](https://www.efbs.admin.ch/fr/themes/therapie-genique/))
termNoteCitation
(a) Sapere.it, Enciclopedia Scienza Biologia Genetica, "genica, terapia" ([Internet, 2021-04-20](https://www.sapere.it/enciclopedia/g%C3%A8nica%2C+terap%C3%ACa-.html)); (b) Commissione federale per la sicurezza biologica, Temi > Terapia genica, 2021-01-04 ([Internet, 2021-04-20](https://www.efbs.admin.ch/it/temi/terapia-genica/))
descriptionCitation
CORDIS - Risultati di ricerca dell'UE, Terapia genica - Il gran dibattito, 1997-10-08 ([Internet, 2021-04-20](https://cordis.europa.eu/article/id/9143-gene-therapy-the-great-debate/it))
descriptionCitation
Le grand dictionnaire terminologique, "génothérapie germinale" ([Internet, 2021-04-20](http://gdt.oqlf.gouv.qc.ca/ficheOqlf.aspx?Id_Fiche=17010858))
descriptionCitation
nach Spektrum.de, Lexikon der Biologie, "Keimbahntherapie" ([Internet, 2021-04-20](https://www.spektrum.de/lexikon/biologie/keimbahntherapie/35721))
descriptionCitation
after KidsHealth, For Parents > Gene Therapy and Children - Two Types of Gene Therapy, 2021 ([Internet, 2021-04-20](https://kidshealth.org/en/parents/gene-therapy.html))
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Outgoing Relationships

property object
seeAlso germline cell
seeAlso germline
inDefinedTermSet Terminology of reproductive medicine
inDefinedTermSet Swiss Federal Administration
has part Keimbahntherapie
has part thérapie génique germinale
has part terapia genica della linea germinale
has part génothérapie germinale
has part terapia genica germinale
antonym somatic gene therapy
hypernym gene therapy
Reliability code Linguistic/formal check completed
termDomain MEDICINE
termDomain BIOLOGY
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Incoming Relationships

property subject
seeAlso germline cell
seeAlso germline
antonym somatic gene therapy
hyponym gene therapy
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